Lower High Cholesterol - User Manual For Humans S1 E16 - Dr Ekberg
good afternoon happy to see all of you here we're going to have some fun here
today I'm dr. Sten Ekberg and this is another installment in our series user
manual for humans and why do we have a user manual for humans well you have one
for your toaster you have one for your hair dryer you got one for your
microwave nobody gave you one for the full that you would be and that's the
most important one so today we're going to talk about cholesterol and this is in
my opinion when we look back at this one generation from now this will be
equivalent to the dark ages there is so much myth and misunderstanding and it's
been so vilified that it's it's unbelievable so we're going to talk
about what it is and what what really is good or bad about it so cholesterol I
call this the the good bad and the necessary so we're going to talk about
what is it what does it do why is it a natural thing and why is there really no
such thing as good or bad cholesterol
it's the greatest hoax sins low-fat diets and we'll look at the cartoon here
and this sort of illustrates the level of understanding a lot of people have no
HDL and LDL were not the robots in Star Wars so we'll hopefully erase our for
awareness a little bit and the history really isn't that important so I'm just
going to kind of race through it but it's important to understand that a lot
of this is coming from not necessarily from a need but from a desire to do
business so 1847 they first found a cholesterol as as a component of a of a
plaque and then a hundred years later they did something called a Framingham
Heart Study of home is a place where they have followed
people for decades and they've traced and studied their their heart conditions
and most of what the heart policy and guidelines that we have come from these
studies so in 1957 10 years into the study they said oh well these people are
having issues we need low-fat diets and then in 1971 they started isolating
different components that they thought could be useful but at this time they
didn't really do it for the purpose of finding cholesterol but they were it's
just part of research so they found something called meta Staten from a
fungus this caused tumors muscle deterioration and death in dogs so they
thought we must be on to something good here and then in 1978 Merck isolated
lovastatin from another fungus so these are related substances and in 1985
someone was awarded the nobel prize for clarifying the cholesterol production
pathway and this is important to understand the body actually
manufactures cholesterol and it manufactures most of the cholesterol in
your body then 1987 Merck releases a anti statin drug called mevacor there's
a six hundred million dollars a year advertising budget and there's some more
guidelines from the government and they're still talking about low-fat then
in 2001 now we're starting to see what's happening with with lobbying that these
companies they're saying well we're giving people these drugs but they still
have high cholesterol so we need to make stricter guidelines and this happens
through login that so the government changed and
because they tightened up the guidelines all of a sudden instead of 13 people 13
million people being candidates for these drugs now there's 36 million
people so through this lobbying they're increasing their market share and what
used to be a healthy level all of a sudden was too high so most of these
levels are artificially and arbitrarily created another thing that we're seeing
change is prior to this there have never been marketing of pharmaceuticals
straight to the consumer that have always been done to the doctors or to
the the health care field but now they're they're bypassing the doctor and
they're going straight to the consumer and they're saying you have this problem
you need this drug go ask your doctor and the doctor doesn't know he says okay
well I guess it's a good thing so now they're starting to put people on drugs
from the pressure of the consumer coming to the doctor instead and that's that's
an enormous increase in pressure so to speak to expand the market for drugs and
in 2010 there were 28 billion dollars in sales straight to 24 staff and drugs and
what they're talking about next is to release these over the counter I saw
some statistic what was it used you showed me one in four people over a
certain age and I don't know exactly what the HD was 40 50 somewhere around
there and what is all this based on well there is the research called a
Framingham study and they observed certain facts and they drew certain
conclusions so we'll go over those the fact was people with heart disease
usually have higher cholesterol than healthy people that's a fact to
atherosclerosis plaques can tane cholesterol 3 these people also
usually have a higher ratio of LDL to HDL cholesterol those who are the facts
that they observed now it depends on how what sort of philosophy and how you view
the body what sort of conclusions you draw from that so their conclusion was
cholesterol causes heart disease and too they concluded LDL is bad and HDL is
good and from this we have these terms of good and bad cholesterol now here's
the problem as it is with with most of the research when when it comes to drugs
and the medical research they do first problem there was only a correlation no
one ever suggested or prove that there's a causative relationship between one and
the other all they did was they observed one and they observe the other so they
said we see these two they must go together and one must be the cause of
the other that has never been the case so they assumed a causative relationship
so here's another thing like I said the body produces most of your cholesterol
so nobody here was asking why is the liver making too much cholesterol
they're just assuming that that you're eating too much of it and that must be
the problem and as usual they blamed it on the DNA there must be something wrong
with your jeans right my favorite analogy for this is to illustrate the
thing between correlation and cause every time there's a traffic accident I
see blinking blue lights so because I see them at the same time they must
belong together and one must be the cause of the other so the blinking blue
lights must cause traffic accidents because I see them
there every time right that's this level of sophistication of thinking the
thinking process that led them to believe that cholesterol causes heart
disease so with this we can say oh well if the blinking blue lights cause
traffic accidents and I see those policemen driving those cars with the
blinking blue lights it must be bad policeman okay bad Fire Department bad
Police Department they're causing traffic accidents and that's absurd like
we can all see and it's equally absurd with the cholesterol so we're going to
talk about why that there's no such thing as as good or bad what are and
here's a question that they don't ask before they put these labels and draw
these conclusions these are questions they don't ask what is it cholesterol
does what is the function of cholesterol are we supposed to have it in our bodies
so first of all cholesterol is a hormone precursor all of the male and female
hormones are built from cholesterol we need that cholesterol as the raw
material to make estrogen and progesterone and testosterone we can't
do it without so the function of our ovaries and testes and adrenals are
stress coping ability depends on cholesterol vitamin D cannot be produced
in the body we get it from sunshine but it cannot be produced without adequate
cholesterol in the body and now they found vitamin D as the number one
vitamin that everybody needs that it's linked to all
sorts of problems when you don't it is needed for digestion the bile in the
liver that helps you emulsifying process fats contains cholesterol and most
importantly now we're getting to it's a component of the cell membrane and when
I can get into detail on the cell membrane but the cell membrane is the
microprocessor of the body it's the brain of the body the cell membrane is
what determines the outside and the inside of the cell is the barrier that
decides what goes in and what stays out so because of that it's the decision
maker in the body in all regards and that's the function of the brain and the
nervous system the function that the reason the brain can makes decisions is
that it has a cell membrane that can tell the difference between inside and
outside and cholesterol is a vitally important component of the cell membrane
so we cannot make proper cell membranes without the cholesterol so the
permeability and the fluidity of cholesterol depends on this so if we
don't have enough then signaling and nervous system function of the nervous
system can suffer if we have a lack of cholesterol it's been linked to
depression and cholesterol is also indispensable for making Milan and
myelin is a fatty substance that surrounds the nerve fiber and this is
like the insulation if you have an electric wire it's always insulated by
plastic well the body does the same thing but it does it with Milan
containing cholesterol so the insulating and signalling properties of the
depends on this and it's it's vitally important for brain maturation so when
they're saying that all these kids are so unhealthy we need to get them on
statin drugs while they're teenagers this would be incredibly devastating
because it would keep their brains from maturing properly ingested versus
manufactured using a complex thirty seven step process so I mean it's 37
steps this is not something that accidentally happens in the body for no
good reason that if it goes through all those steps the body has a reason to
make this stuff the liver produces approximately a thousand milligrams a
day while another two or three hundred milligrams are ingested on average
however this ingested cholesterol the stuff that you eat is not absorbed very
well so it's actually even though you eat two to three hundred milligrams not
all of that is getting into your body so that makes the importance of the
ingested cholesterol even less in comparison but furthermore cholesterol
because it's so important and most important substances in the body they
circulate so the body releases them at some point so the gallbladder releases
cholesterol into the intestine but because it's an important substance it
is being reabsorbed so we're saving so we don't have to make so much of it all
the time the body is economizing with this important substance and because of
all these factors there is virtually no effect on the cholesterol level in your
body of the cholesterol that you eat because when you eat more of it your
body is going to make less when you eat less your body is going to make
or so the ingested cholesterol has virtually no bearing at all on the
cholesterol in your body okay so what what is it that that does determine well
let's look at a little more specifically what they do these guys LDL and HDL
stands for low density lipoprotein and high-density lipoprotein so as the name
implies light bulb protein is something that contains lipids and protein it has
fat and protein in it but it has different components so depending on how
much protein it has it's either high density or low density so something
that's low density the LDL it's lighter because it has more fat and less protein
and and vice versa so what these carriers what these do they are carriers
they're their vehicles it's like a bus and the purpose of that bus is to
transport things so LDL and HDL these lipoproteins are carriers they're like
buses and what they do is they either carry cholesterol out to the tissues if
the tissues need cholesterol or they bring cholesterol back if the body has
had enough so LDL means that the bus is already full of people it's already full
of cholesterol so if you need to transport these people some place and
drop them off that's the function of that bus then if the people are out
there and then they need to be picked back up then you need
sent an empty bus so that you can pick them up and bring them back this is
exactly what LDL and HDL does there's nothing good or bad about it if the body
needs cholesterol in the tissues deliver make more LDL so it can deliver
cholesterol to the tissues if there is enough at the tissues or too much then
the body makes HDL so we can bring the cholesterol back to the liver for
reprocessing so that's the purpose there's no good or bad that's just what
it does it's a carrier and the volume makes whichever one you need at the time
what's the situation then where the body makes more LDL or HDL well what's the
purpose the purpose of cholesterol is like we said it's all of those hormone
functions and all that but remember it's part of the cell membrane so anytime
that we have damage in the body the body needs more cholesterol to repair the
damage and what is it that causes damage primarily in the body it is inflammation
and they're finding out more and more and more and more that all these
degenerative diseases from Alzheimer's to heart disease diabetes is a state of
low-grade inflammation heart disease is an inflammatory condition and when you
have inflammation in the tissues and you get cell damage to the cell membranes
and you need to repair those cell membranes the body makes more LDL
cholesterol to deliver it to the tissues so the LDL is not the bad guy it's the
inflammation so if we want to change anything about this then we just
need to find out what are the lifestyle factors that are causing the the high
inflammation and one thing that we talked about in this office is stress
because stress has been linked to virtually every disease and it's linked
in this function as well that you're sitting at a picnic you're having a good
time and your your stress and your healing your sympathetic and your
parasympathetic are in balance and then the grizzly bear shows up for your
picnic and now things are not so peaceful you get into a state of stress
and some of the things that will happen is your heart rate goes up your blood
pressure goes up your muscle tension goes up your blood sugar goes up but one
more thing that happens is you check out those claws on the bear and they look
pretty sharp so your quality you're infinitely smart body says there's
probably going to be some bleeding before this is all over so just in case
I'm going to prepare to stop the bleeding and in order to stop bleeding I
have to increase the blood clotting factors and what's included in blood
clotting factors cholesterol is part of that cascade and once we have the damage
we're going to need cholesterol for the wound healing to create new cell
membranes to create all of that so whenever as soon as we see that grizzly
bear we have an increase in LDL cholesterol because the body is planning
ahead and saying we better deliver some cholesterol to the tissues just in case
so even though we don't have them any grizzly bears we have quite a bit of
other stress okay so when you see that grizzly bear and your LDL is going on
your body is doing exactly what it's supposed to you are not missing a statin
drug your body is behaving exactly the way it's supposed to
stress so the problem again is stress and inflammation it's not about the food
that meat unless the food of course creates inflammation that's a different
story but it's not about how much cholesterol is in there what are some of
the ways to bring it down obviously reduce the need for it so even though
cholesterol isn't good or bad obviously having high cholesterol is not a good
thing because it means that we have inflammation in the body so as we get
healthier as we learn how to be healthy meaning eat better move better feel
better as we talked about in our long series of user manual then inflammation
goes down and we need less cholesterol to repair the damage the other way to
bring it down is to use a statin drug a cholesterol-lowering drug and what does
it do what's the mechanism well the statin drug interferes with the livers
ability to manufacture cholesterol so your body is saying we want this
cholesterol and it signals the liver to make some more and we take a drug that
destroys delivers ability to make it so we have to basically choke the living
daylights out of the liver and if you notice on all the commercials what do
they say never ever take this if you have any problem with your liver because
we're going to choke it some more so if it had any sort of problem then we're
going to squeeze the life out of it so you have to have a perfectly healthy
liver so it can sustain the damage we're about to do to it that's why they say
that and what's the effect of the drug as well it's going to lower your
cholesterol so it's going to look on the blood test
is going to look like a good thing happened but what really happened is you
still add the stress you still have the inflammation you just don't have the
ability to make the cholesterol so you're not healing yeah and this is how
most medical research is done they don't ever look at are you getting healthier
they're looking at one measurement they're looking at blood pressure or
cholesterol or some some aspect and they're saying can we change that one
aspect they don't care at all about anything else that they might be
changing in the process Jenny's really don't know affect that yeah I'm missing
with one thing yes yes and we'll do another talk on on drugs and their their
mechanism just so you can see a little bit more that what are some of the stat
and side effects liver damage muscle damage and what's one of the more
important muscles it's the heart and it can affect memory concentration and
cause depression it can create pain and peripheral neuropathy again if you don't
have the cholesterol to repair the damage now your nerves are going to get
yet have issues sleep problems sexual dysfunction fatigue if you don't have a
cholesterol to manufacture your sex hormones then you get sexual dysfunction
and one thing that's really important that we've talked a lot about is
mitochondrial function is absolutely guaranteed that these statin drugs will
interfere with your body's ability to use Co Q 10 so if you ever ever get on a
a statin drug for whatever reason if you if you get talked into it make sure you
double up and triple up on your coat 10 because your body is going to need it
and with that reduction of coq10 of course your body the mitochondria are
not going to be able to make this the energy that's so essential for for every
cell function and what's where you have most of your mitochondria well in the
most active organs which is the brain the heart and the liver and then the
right one Co Q 10 yes yes yes the ubiquinol it the active form so here's
here's just a little bit of what I mentioned up front that the guidelines
that the drug companies they obviously want to make money so the more clients
they have the more the potential target market the better for them so they're
lobbying they're saying hey we're doing all this stuff people are still getting
heart attacks we must we must tighten the guidelines so over the years they
manage to change these guidelines so that more and more and more people get
in the into the target zone become a target market so then this guy at the
fast food dining table says my heart has survived 16 girlfriends seven fiance's
and four ex-wives you think my heart is afraid of a cheeseburger so we want to
start understanding the body a little bit differently all of the traditional
risk factors the things they talk about as risk factors they're not really risk
factors at all some of them are quite ridiculous actually and being male
that's not a risk factor it's a correlation again smoking it's not a
risk factor it's because increases free radicals and decreases oxygen
hypertension is not a risk factor it's an association it's it's just another
effect of poor health that's that's observed in correlation diabetes the
same thing family history got nothing to do with it HDL of course it's it's
another effects of all of the things that they're talking about or not the
risk factors there's just other things that you observe in conjunction with
poor health and we need to start understanding what the true risks are if
we're ever going to get to the source of the problem the real risk factors are
free radicals inflammation and degeneration what are they caused by
chemical stress structural stress and emotional stress it's what we talk about
in all the other installments of the series and we talk in details about how
each of the work and what we can do about them so that is all we have on
cholesterol and we encourage you to learn more and come to other other talks
that we have and feel free to ask any questions