Keto Dangerous? (Studies vs Real Life)
Keto diet and longevity. So most people
realize that keto is great for burning
fat and losing weight but then they hear
on the other side a lot of opponents
claiming that the body needs
carbohydrate and if you cut it out too
extremely you won't live as long and
it's unhealthy and side-effects and so
forth so let's take a really close look
at the mechanisms and what's really
going on here. So there's a lot of
studies out but one review study I found
which was interesting was ketone bodies
mimic the lifespan extending properties
of caloric restriction so back in 1935
they found out that rats lived longer if
you fed them less so they reduced their
diet they reduced their caloric intake
basically starved them by feeding them
30 to 50 percent less than a normal rat
would eat and they found when they did
that continuously then the average
lifespan of the rat went from 500 days
to 820 days so about a 60% increase in
longevity and ever since then there has
been this association between calorie
restriction and longevity and they've
been able to duplicate this in a number
of different species so it's not just
like rats they've done it with tiny tiny
things like yeast or nematodes or fruit
flies but they also done it with mice
and primates so what is it about calorie
restriction that makes you live longer
that's what they try to figure out and
they had different theories maybe it's
that the cells turn over slower there's
less wear and tear maybe it's that the
body fat is reduced when you starve the
rats
maybe the fat is so bad that it it's to
sit on your body that it it does bad
things and makes you live shorter maybe
it's the inflammation because we all
know inflammation is is bad and starving
reduces overall inflammation may be body
temperature because once you restrict
once you starve it the body thinks I
don't have as much to burn so I better
conserve it and turn down the furnace I
can last a little longer or insulin
they've noticed that a lot of these
things seem to do with insulin so let's
look at insulin just a little bit closer
and realize that insulin is what they
call a mitogenic hormone what that means
is it increases mitosis and mitosis is
cell division or cell replication so
anytime a cell makes a copy of itself
then it divides one time and they found
that you only have so many copies
available it's called a hayflick limit
and it's tied in to longevity and
telomeres and so forth which is a
genetic marker of how long you can live
based on these cell divisions and we
found that insulin increases the
turnover rate it increases the rate at
which cells make copies so that can be
good in terms of of growth or repair but
it can be really really bad because it
also increases cancer because it makes
the cancer cells turnover and replicate
faster too and it's been associated with
atherosclerosis because it makes the
first of all it increases inflammation
and a lot of the plaquing is in response
to that but it's also been shown to
increase the formation of the a
thoroughness of the atherosclerosis
which leads to heart disease and of
course it's been linked to aging because
insulin if it tends makes the cells
turnover faster then it increases the
rate of aging so when we look back
because they could never quite figure
out which one of these is it but once we
look at this we realize that insulin has
to do with virtually every single one of
them because insulin increases the
turnover insulin is a fat storing
hormone insulin is inflammatory
increases in
Meishan body temperature I don't know if
that would be directly linked
specifically to insulin and of course
the insulin is linked to insulin so most
of the reasons for the mechanism is tied
to insulin so what happens when we storm
the rats well there's two things that
always go together first is that we
reduce insulin because insulin is there
to process carbohydrates and when you
eat less
you're gonna eat less carbohydrates
there's less need for insulin you're
also going to increase ketones
so these always go together insulin and
less insulin and more ketones they
always go together
and it is always healthy it's always
favorable except in one case and that is
in type 1 diabetes when the insulin goes
to 0 and then the ketones go sky-high
which is a pathologic disease condition
as long as you have the ability to make
some insulin then it is healthy to
increase the ketones and there's
different ways to increase the ketones
so we know it happens in starvation or
in fasting which is prolonged periods of
not eating whether it's voluntary or
involuntary fasting is generally
considered voluntary and starvation's
considered involuntary exercise will
increase ketones and low carb diets with
increased ketones so the question then
becomes which one is it that produces
the beneficial results is it less
insulin or is it more ketones and we
don't have a clear answer on this but we
don't really have to worry about it
because one always follows the other so
if we get one we always get the other
they both seem to have tremendous
benefits to themselves if we reduce
insulin we reduced 95% of all
degenerative disease when we increase
ketone
we tend to get certain observable
benefits as well we can treat various
different conditions with it we know
obesity and diabetes improve with
ketosis but they've also found a lot of
other neurological conditions that have
pretty much been resistant or they
didn't get any results at all until they
tried ketones and things like
Alzheimer's and Parkinson's and ALS
really severe neurological diseases tend
to get better with more ketones one more
thing that ketones do is they're
metabolized differently inside the cell
inside your cell you have mitochondria
which produce most of the energy for you
the vast majority of all energy used is
in the mitochondria and they have
different pathways and it turns out the
ketones go through a more efficient
pathway they can bypass a step or two
and therefore they can produce more ATP
or more of your energy currency per unit
of oxygen so it's more efficient and it
produces less damage less oxidative
damage by burning ketones and burning
other sources of fuel and one thing we
have to realize which this is my opinion
based on a bigger perspective and a way
of observing things naturally is you
don't improve all these different
conditions you can't improve such a wide
variety of condition by making someone
less healthy so the biggest detractor
for the the opponents the biggest
argument is that sure it helps for for
obesity and diabetes but we don't know
the long-term effects we it's it's bad
for this or you have to have carbs or
fat is is bad and they're pulling these
statements but they can't really put the
picture together but the one picture I
want to keep in mind is if it brings
together if you'd improve such a wide
variety of conditions then
it's not a bad thing so ever since 1935
when they first figured this out the
calorie restriction has been a huge
topic it's been something that people
say oh yeah if only I could do that
if only I could restrict my calories for
the rest of my life then I would live a
whole lot longer but the problem is when
you starve yourself then unless you want
to be a rat and they put you in a cage
and just feed you half of what you want
to eat you're not going to be able to
keep it up because hunger doesn't feel
good the vast majority of people are not
going to be able to keep it up so we
know that calorie restriction improves
insulin and ketosis reduces insulin
increases ketones but you get hungry
so wouldn't it be nice if there was a
way that you could reduce insulin and
increase ketones
without going hungry and I know I've
heard about something I think there's
there's something I heard that could do
that but no wait wait here it's coming
to me
oh yeah the ketogenic diet that's what
it is because when people do that they
reduce insulin they increased ketones
but they don't go hungry and this is not
so easy to understand for people who
haven't tried it but once you try then
you notice that your body wants fewer
meals because fat is very satisfying
then you can go longer between meals so
in the end you end up eating a little
bit less maybe not less calories
probably a little bit but maybe not but
the main thing you get is reduced
insulin and increased ketones so you get
these anti-aging benefits you get all
these health benefits because it is
primarily about
the insulin and possibly some about the
ketones but it's certainly not about the
calories the reducing of the calories
only results in changed insulin and
ketones it's not the calories per se so
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many people as possible healthy we want
to help people understand the true
principles the true mechanisms around
health not just memorize a laundry list
of things to do because that's
short-lived but once we understand the
mechanisms the big picture then we can
start creating a long term healthy
lifestyle so leave your comments and
questions below and thanks for watching
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