10 Urgent Signs Your Body Needs Magnesium
Magnesium is critical in the production of energy in the body. Everything that
your body does requires energy most modern degenerative disease which kills more people
than anything else all heart disease and strokes and a lot of dementia if we don't
have enough magnesium now it's difficult for the body to balance these responses. Hello,
Health Champions. What if your most stubborn health problem came down to something as simple
as a magnesium deficiency? And that's very possible because magnesium functions as a
co-factor in over 300 enzymatic reactions. That covers virtually every function in your body,
and today, we're going to talk about the top 10 signs that you may be deficient in magnesium.
Sign number one is muscle cramps. A lot of people associate muscle cramps with minerals
or with magnesium, and there are several minerals involved, but magnesium is the
critical one in balancing all the others, such as sodium, potassium, and calcium. So,
calcium is involved with contracting the muscle in one step of contracting muscles,
and then magnesium counteracts calcium. So, magnesium competes
with calcium for these binding sites, and then magnesium allows that muscle to relax.
Sign number two is fatigue and weakness. Magnesium is critical in the production
of energy in the body, and energy is called ATP. That's the energy currency that your body uses:
adenosine triphosphate. So, what is that? Well, you have a little sugar complex called adenosine,
and then this adenosine is bound to phosphate groups. If we have one phosphate group,
it's called adenosine monophosphate, and that's a low-energy state. It's relatively stable;
this is not often going to break apart. But then we have a high-energy bond that I like to think
of as a spring. It's kind of spring-loaded; you load it up with energy, and then when it releases,
then that spring discharges its energy. So, we have two of these; that's called adenosine
diphosphate, and that's a higher energy state but it's still a low-energy state compared to
adenosine triphosphate. So, this is the energy currency that your body uses. Everything that your
body does requires energy, and the way it gets this energy is that we break down food, and we
move around electrons, and these electrons cause phosphate groups to bind on to this adenosine, and
when we have three of these phosphates, we have a spring-loaded system that's just waiting to spring
loose, like a bow and arrow, basically. And then as soon as this phosphate group is bounced off,
now we use more energy to put it back on, and then we do this over and over and over,
and we do this trillions and trillions of times every second because everything
in the body requires this energy currency. And there are three different primary ways
that magnesium participates in this. First of all, this molecule is stabilized by magnesium;
most of the ATP is circulating inside the cell as a magnesium-ATP complex. But then there's
also several steps where magnesium is critical for the function, for the biological activity of ATP,
for expressing this, for binding it, and unbinding different complexes. And the third way is in an
enzyme called ATPase. So, in order for this spring to come undone and release its energy,
we need an enzyme called ATPase. "ase" is just an ending they put on words to indicate that it's an
enzyme, but this ATPase is magnesium-dependent. So, out of these 300 ways that magnesium acts as
a co-factor to enzymes, here are just a few that are involved with energy production.
So, one reason magnesium deficiencies are so incredibly common is that magnesium is
notoriously difficult to absorb. But not only that, we make it even harder because there are
some modern lifestyle factors, and I'll mention a few of these. The first one is that we eat a lot
of high-phosphate foods, and even though phosphate is necessary, and it's the same phosphate that
we just talked about with the ATP, adenosine triphosphate, when we eat too much, then this
phosphate binds to the magnesium and keeps us from absorbing it. So, inside the cell, magnesium helps
stabilize this ATP complex, but in the digestive tract, it's a bad thing because it keeps us from
utilizing it. And some of the places where we get excess phosphate are things like soft drinks,
fast food, processed meats, and baked goods. So, you don't really have to worry about the natural
phosphate content in good whole food, but it's with the processed foods that we can get too much.
Sign number three is metabolic disease. And now, of course, we're talking about insulin resistance,
which is at the core of most modern degenerative disease, which kills more people than anything
else. So, all heart disease and strokes and a lot of dementia are caused by insulin resistance,
and magnesium may not be the primary cause of this, but it is still critically involved with
this because magnesium increases the activity of the insulin receptor. So, in order for insulin
to work, it has to bind to this insulin receptor, which acts like a key, and with magnesium present,
we get more of this activity, letting glucose into the cell. So, magnesium deficiency is one factor
that keeps people insulin resistant, that keeps insulin from working properly. Another aspect of
this is number four, which is high blood pressure and irregular heartbeat, or heart arrhythmia. So,
in order for muscles to contract and relax appropriately, we need a balance of different
minerals, and the key to contracting is called calcium, and then we need magnesium
to relax this. And this, to me, is one of the most fascinating aspects of human physiology. So, there
are two proteins in a muscle, and one is called actin, and another one is called myosin. So,
we have these two proteins, and because of calcium and magnesium and ATP, we have this little protein
called myosin that has kind of like a hinge on it, and then with calcium, it binds the myosin to
the actin, and then because of ATP, it performs what's called a power stroke. So, this protein
changes shape and kind of cranks forward, so it ratchets the protein, the actin, over, and we get
movement. And when we have millions and millions, hundreds of millions of these little proteins,
that's what creates muscle contraction. That's how we can shorten a muscle. A muscle can never push;
it can never exert energy to become longer. It can only pull, and then magnesium is critical for
causing this muscle to unlatch, so to disconnect, so it can do this movement over again. So,
it's a balance between calcium and magnesium, and if we don't have enough magnesium, that's what
causes muscle cramps, but also, of course, the poor timing of muscles when that is necessary.
So now, we can get high blood pressure because the muscles in the blood vessels don't relax, and we
can get heart arrhythmias because they don't time things right. And besides decreased absorption,
like we talked about, our modern lifestyle can also cause excess excretion, that we get rid of
too much. And now, we have some things that if we use them in excess, such as coffee and alcohol,
now that can make the kidneys flush out excess amounts of magnesium. And then we have something
called stress, which increases our levels of cortisol, and high levels of cortisol can also
flush out excess magnesium. And then, of course, there's dozens and hundreds of medications that
also interfere with the body's ability to balance these minerals and cause excess loss of magnesium.
Sign number five is insomnia and sleep problems. And just like magnesium can have a calming effect
on muscles, it can also have a calming effect on brain cells. So, brain cells signal by electric
potentials, and when they get over-excited, then magnesium can calm down, can stabilize that nerve
cell, that neuronal membrane. And again, it does this just like the muscle because magnesium is
a calcium blocker. So again, calcium is not a bad thing; it helps send signals,
it helps activate things, but we need to find that balance, so it doesn't get out of control. And if
we have a magnesium deficiency, now there may be more excitation than relaxation. And furthermore,
magnesium also helps regulate melatonin, which, of course, is the hormone that helps us fall asleep,
that regulates our sleep cycles. But there are even more ways that our modern lifestyle keeps
us from getting enough magnesium because of modern mass farming practices. We have caused widespread
soil depletion. So, what happens is when the plant grows, it binds minerals inside the plant,
and it absorbs these from the soils and fixes them in the plant. And then we move the plant away to
some distant location to consume it, and then we immediately go back to sowing the field again for
next year's harvest. But now, we took lots and lots, we took dozens of minerals out of the soil,
but we only typically put three back. And the three are the ones critical to make
a new plant big and juicy. It may not have any flavor; it may not have any nutrients,
but at least it looks good. I talked in another video about the epidemic deficiencies, and about
how important vitamin D is, and it's probably the only nutrient that can match magnesium in terms of
how important it is, and how common a deficiency is. And now we also learned that a high or a low,
like a very excessive or a very deficient level of vitamin D, contributes to magnesium deficiency.
Aging is another big factor because as we age, certain things like nutrient absorption and
digestion work less efficiently. And then, of course, medication again, like we mentioned,
may cause less absorption and more excretion. And as we age, typically, people consume more
and more medication. Another factor that is often overlooked is the health of our gut. So,
if we have GI disorders, gastrointestinal problems such as IBS, which is irritable bowel syndrome,
where we often alternate between constipation and diarrhea, it's very easy to get an upset stomach;
that's just a general term for irritation. But then there's also IBD, which is inflammatory
bowel disease, and these are more serious. These will cause destruction often of the
intestinal membranes, and these are things like Crohn's and celiac disease. And if we
have either one of these two, then there's going to be irritation and inflammation in the gut,
which is going to dramatically reduce our ability to absorb and utilize nutrients,
even if we eat the best food. It may not be utilized properly. And even if we don't have
anything as severe as IBS or IBD, a lot of people have an imbalance in their gut flora,
and that alone can prevent us from absorbing nutrients properly.
Sign number six is anxiety and depression. And magnesium will help regulate our
neurotransmitters, the chemicals that the brain uses to send signals. And it also
affects what's called the HPA axis. The HPA stands for hypothalamus-pituitary-adrenal axis, and the
hypothalamus is our master regulator. It senses pH and oxygen and all these different things,
the hormone levels in the body, and then it tells the pituitary, which is our pharmacy,
which sends out hormones to tell the different body parts what to do. And of course,
we have the adrenals that respond to stress. So, it responds to the messages from the hypothalamus
and the pituitary, and this is how we can have a stress response at an appropriate level. But then,
of course, we need the body to be able to balance this and turn it off appropriately,
and a lot of this has to do with the health of the frontal lobe, like I've talked about
in many videos. But if we don't have enough magnesium, now it's difficult for the body to
balance these responses. Magnesium also supports neuroplasticity, which is the brain's ability to
change things. The brain is always adapting and changing and switching things around, by making
new connections and breaking down old connections. That's how we learn things; that's how we can
stabilize the brain and help the brain adapt. And again, magnesium supports this neuroplasticity.
Sign number seven is osteoporosis. And magnesium is critical in so many ways for
this. First of all, magnesium is a component of the bone matrix, of the bone tissue. But
magnesium also acts as a signaling molecule and regulates multiple functions. So, there are two
types of bone cells that build and break down bone, and both are equally important because,
in order to have flexible and elastic and strong bone built in the right way, we have to build bone
and constantly break it down and remodel. That's how we get healthy bone, and magnesium influences
the osteoblasts that build up the bone. But magnesium also affects calcium and vitamin D
metabolism, and of course, calcium is critical to bone because it's the prime component, and vitamin
D is also necessary to build bone and to absorb calcium. And magnesium influences and regulates
both of these. But it doesn't stop there because magnesium also helps regulate the hormones that
signal for building or breaking down bone. And the two hormones are calcitonin, which is putting
calcium and minerals into the bone that increases the density and the tone of the bone, and then we
have parathyroid hormone or parathormone, made by the parathyroid gland, that breaks down bone.
And again, both of these are critically important. It's not just that building bone is a good thing,
and breaking down is a bad thing, not at all. We need the balance to get healthy bone, and we
probably underestimate just how common a magnesium deficiency is. And the couple of reasons, first,
like we said, it is very poorly absorbed, and then there are all these different factors that keep
us from absorbing it even further. But on top of that, it is almost never measured on blood work,
and then different people use different ranges. So, typically, the lab range, the general range
that you get on a blood test is going to be 1.6 to 2.3 milligrams per deciliter. But most of
the doctors in functional medicine, who actually work with this kind of stuff, they will probably
say the optimal level is 2.2 to 2.5. But let me give you a few examples. So, in one study, they
defined a deficiency as less than 1.46 milligrams, which is the same as 0.6 millimoles. So, if you
get your results in millimoles, then the way to convert it is just to multiply the millimoles by
2.43. This is millimoles per liter times 2.43 is milligrams per deciliter. And in one study,
they found that out of all the people who were hospitalized, 12% of them had less than 1.46,
which is a huge, huge step down from the optimal range of 2.2. And when they checked the people who
were really, really sick in the Intensive Care Unit, now, over 60% of those people had levels
that were extremely deficient. In another study, they defined deficiency as less than
1.9 milligrams per deciliter, and now they found that 30% of the entire population was under that
level. And that's typically what I find when we do blood work because we test magnesium on everybody,
that it is extremely common for people to be under two, or even under 1.9. But here's where
it gets really interesting because when they checked with the same criteria, less than 1.9,
and they checked post-menopausal women with brittle bones or osteoporosis, now, over 80% of
these women were below that level of magnesium. And when they checked in the same study,
people with poorly controlled type 2 diabetes, 75% of those people had less than 1.9. So, it doesn't
necessarily say that magnesium is causing these conditions; it could be the other way around,
that people who have a disease or a problem like this are really poor at utilizing. But either way,
what it tells us is there's a very, very strong association, and it would be extremely important
for people in these categories to supplement and make sure that they get enough, that they
counter as many as possible of these modern lifestyle factors that deprive us of magnesium,
and also supplements, they can start building up those levels. And I don't have an exact number,
but my guess, and based on what I see in my clinic, is if we use the optimal level of 2.2,
it is probably more than 60% of the population that is below that optimal level. But there's
one more thing we really need to understand to see how far-reaching this problem is, and that
is when we compare the serum level, which is what we measure in the blood, versus what's inside the
cell because that's where magnesium performs these 300-plus co-factor functions. The total
amount of magnesium in the body is about 25 grams, and out of that, the muscle and bone will contain
22 to 24, for about 90%. All the other cells in the body combined will hold about 2.4 grams,
which leaves us with what's floating around in the blood, in the serum, is about 2.2 mg
per deciliter, so a total of about 100 mg, or 0.1 g. So, what does this mean now? Well, it is very
important for the body to maintain certain levels of calcium and magnesium in the blood. So, we have
these hormones that will pull minerals, including magnesium, from the bone and from the muscles,
and then we can maintain certain blood levels. It may look on the surface because the blood serum
level of magnesium is normal, but that's only 0.1 gram out of the whole body. So, it's very possible
to have a normal serum level but be deficient intracellularly, that the cells don't have enough
where all this work is performed. So, this means that deficiencies are probably even more common
than we ever thought. And again, I don't have a number, but I would suspect that it's at least
80% of people that are deficient, meaning that they could benefit from eating more magnesium,
whether it's a supplement or food. Now, here was a really interesting paper that I found.
The title was "Subclinical Magnesium Deficiency: A Principal Driver of Cardiovascular Disease and
a Public Health Crisis." And this was published in a journal called "Open Heart," which is associated
with the British Medical Journal, which is one of the most prestigious medical journals
in the world. And there are a couple of words we want to pay particular attention to here,
to see just how profound this is. And that is "subclinical," that means that the level of
magnesium deficiency is so slight that we're not having any effect; we're not having any noticeable
symptoms from this yet. And the other word is "principal," which means that even at these slight
levels of magnesium deficiency, it is a leading or prominent cause of cardiovascular disease in a
public health crisis. Those are very, very strong statements. The recommended daily amount is about
300 to 400 milligrams of magnesium per day. The first few are magnesium oxide, magnesium chloride,
and magnesium sulfate, also known as Epsom salt, which typically you're not going to ingest,
but it's used for baths and for enemas because it's a very powerful laxative. Now, what these
three have in common is that they are inorganic, meaning that they don't have any carbon. So,
things that are alive, like plants, they are typically going to bind magnesium in some form
of carbon molecule, and then it's called organic. But these are nonorganic, and that means that we
can't really utilize them much; they're usually very poorly absorbed, and because of that,
they are very powerful as laxatives, meaning they speed up the gut. And if you're constipated,
a lot of people use these to flush things out. And then there are several that are very common as
supplements. The most common is magnesium citrate because it's inexpensive and it works pretty well.
But then there's also magnesium glycinate and magnesium malate. And what these have in common
is they are organic, meaning they're binding to a carbon, to something that was alive. And these, of
course, will be doing the opposite; they're better absorbed. That's why we use them as supplements,
and they have less of a laxative effect. But out of these three, the magnesium citrate probably has
the strongest laxative effect, but not nearly as strong as the inorganic, whereas magnesium malate
is known for not having much of a laxative effect. And then there's a new one called magnesium
L-threonate, and this is promoted as a brain nutrient because it is known to be able to cross
the blood-brain barrier. Now, what we're going to keep in mind is that the ones on the bottom of the
list, the bottom four, they're more natural than the top three. But all of these are still created
in a lab, which means that they're going to be varying degrees of absorbability and tolerance
between people. So, sometimes you just have to try different ones and see what seems to work. What I
have found in the clinic is that there's a product that is 100% plant-derived that we use with really
good results; it's called Standard Process EZ Mag. And if you read the labels, you're going to
notice that it's a little bit lower dosage than a lot of these others because they're isolated
and sort of manufactured, whereas EZ Mag is a pure plant product. And because of that,
it's going to be a lower dose, but it's going to be much better tolerated and probably much better
absorbed. So, a smaller dose is probably going to go a long way, and in the clinic,
it seems to work for most people. So, I'll put a link down below if you want to try that one out.
Sign number eight of a magnesium deficiency could be headaches and/or migraines. And
we talked about these mechanisms before. Magnesium supports neurotransmitter function,
which is the overall signaling, but also it controls muscle relaxation,
which has to do with vasodilation and vasoconstriction, how much the
blood vessels tighten up and release because that is the central mechanism in a headache.
Sign number nine is constipation. And this is the same mechanism again, and it really helps
us appreciate how important muscles are, not just the skeletal muscle that we use to move body parts
on purpose, but all the other muscles that are not under voluntary control, like your heart and your
blood vessels and your GI tract, your intestines. They operate by something called smooth muscle.
And in the GI tract, that smooth muscle, the constriction of the muscles in the intestinal
wall, is what moves the food through, that churns the food and mixes the food, and then keeps moving
it through. And that's called peristalsis. If we don't have enough magnesium, then we can't really
regulate these muscle contractions and relaxations appropriately and could lead to constipation.
Sign number ten is numbness and tingling, which is an abnormal sensation. It's a form of distorted
sensation when the brain either gets the wrong signals or interprets it wrong. And this has to
do with electrolyte balance. And like we said before, magnesium is critically involved with
regulating the other electrolytes. And the primary electrolytes involved in signaling
are sodium and potassium. Numbness and tingling is also dependent on neurotransmitter function,
which we talked about before, but also on blood circulation. Poor circulation can create numbness
and tingling, and this has to do with magnesium's ability to regulate muscles, muscle relaxation,
muscle contraction, and therefore also in setting vascular tone, meaning the tightness
and relaxation of blood vessels to determine how much blood is flowing through a blood vessel.
But I had to throw in number 11, which is chocolate cravings. And here, you're all going,
"I knew it. I knew there was a reason. I knew there was a legitimate reason for me
to crave and eat that chocolate." And chocolate may not be a terrible thing,
but if you have severe cravings, it could be magnesium, but it is much more likely
that you're eating milk chocolate, which is extremely addictive. So, let's just compare
milk chocolate and dark chocolate and talk about which one you really want to crave.
So, milk chocolate, first of all, is over 50% sugar on average, and that's probably
the number one thing that you're addicted to. Then, of course, it has milk in it,
and then it has some emulsifiers and fillers and flavoring agents, which is maybe around 5%,
and then the cocoa portion, which is where the vast majority of the magnesium would be,
is only about 15% in milk chocolate. In Hershey's, I think it was like 11%. So,
you're not getting a lot of magnesium, a lot of cocoa, in that type of chocolate. So, if you're
going to eat chocolate, if you want to justify it, then I would suggest you eat the dark chocolate,
at least 70%, but even better, 85%. And most of that is a matter of habit. If you stop eating
sugar and processed foods, then the dark chocolate is going to start tasting better and better. And
the way you want to understand dark chocolate is that it really only has two main ingredients,
and that's cocoa and sugar. So, if the package says 85% cocoa, that means it has 15% sugar. Now,
not only is that much, much less than milk chocolate, but it's also much less addictive,
and it will satisfy you much, much quicker. So, while it is very difficult to have a piece of milk
chocolate and stop, it is very possible with dark chocolate. Now, the lecithins, the emulsifiers,
the flavoring agents in dark chocolate are going to be minuscule. It's going to barely be there
compared to milk chocolate. So, the rest is going to be cocoa, which is where anything that you've
ever heard would be beneficial about chocolate, whether it's magnesium or some other thing in
there, it's going to be in the cocoa and not in the other components. So, if we compare the
magnesium content in 85% dark chocolate, we see that it's about 225 milligrams per 100 grams. Now,
you probably don't want to eat 100 grams, but if you have about 1 ounce, again, 28 grams or so,
you're still getting a substantial amount, 63 milligrams, which is more than a serving of most
other foods. So, it's not a bad thing, whereas if you eat the milk chocolate, now you're only
getting 60 milligrams in an entire bar. So, if you manage to keep yourself to just eating 1 ounce,
you're getting a measly 17 mg of magnesium, hardly worth it for all that sugar you just consumed.
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