AMA #6: Eye Health, Why We Yawn & Increasing Motivation

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ANDREW HUBERMAN: Welcome to the Huberman Lab podcast

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where we discuss science and science-based tools

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for everyday life.

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[MUSIC PLAYING]

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I'm Andrew Huberman, and I'm a professor

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of neurobiology and ophthalmology

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at Stanford School of Medicine.

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Today is an Ask Me Anything episode, or AMA.

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And for those of you that are not Huberman Lab podcast

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And now without further ado, I will answer your questions.

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And as always, I will strive to be

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as thorough as possible, as clear as possible,

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and as concise as possible.

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The first question is about eye health,

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in particular eye health protocols

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for people that are aging but eye health protocols

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for people in general.

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The question is, I'm noticing that my vision,

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both close and far, is deteriorating.

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What are the best eye exercises, eye health behaviors,

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supplements, et cetera for the aging eye?

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So the answer I'm about to provide

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applies to everybody regardless of age,

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which is, you want to make sure that you view things both close

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up and far away across your day.

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Many, many people nowadays spend a lot of time

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looking at their smartphone, looking at the computer screen,

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looking at books and paper, in other words,

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looking at things somewhere between 9 inches away

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from their face and their eyes, maybe 2 and 1/2 feet away

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from their face and eyes.

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This is an unprecedented event in human history,

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as far as we know, because it wasn't

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until the advent of the smartphone

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that we've spent so much time looking at screens

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at close range relative to looking

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at things at further distances from our face

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throughout the day.

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In fact, it should come as no surprise

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that the incidence of myopia, of nearsightedness,

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is increasing dramatically around the world

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but is increasing particularly fast in children

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and in young adults and even in adults

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who are viewing things at very close range, so 2 and 1/2 feet

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or less.

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Now, I am not saying that viewing things

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at 2 and 1/2 feet or less is bad for your eyes, that is simply

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not the case.

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However, if you want your vision to be maintained or even

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improve, it's going to be very important

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for you to view things at a distance

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as well for ideally several hours per day.

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Now, I realize some people just simply won't accomplish this.

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In fact, I'd like everyone to just take a moment

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and do a rough estimation in your head

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of how much time during your daytime activities

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you are viewing things at, say, 2 and 1/2 feet or 3

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feet or less, so smartphone, computer screen,

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paper, books, et cetera, versus viewing things

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that are 4 feet away, 8 feet away,

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so maybe conversation across the table with another human being.

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Remember those?

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Some of us are doing that more now

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that we seem to be emerging from this whole pandemic phase.

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However, many people are still mostly just viewing

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things within very close range.

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And, in fact, if you were to ask yourself, how much time do

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you spend looking at things at the distance of many hundreds

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of feet, or taking a walk where you're not looking

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at any screen and you're simply letting

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visual images or the visual imagery

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rather pass by on your eyes, I think for most of us

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that number is getting progressively smaller

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and smaller with each passing year.

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So this is an issue because the structure of the eye

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is such that the lens of the eye can move,

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but also that the length of the eyeball from front to back

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is actually impacted by how close

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or how far you happen to view things

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during the course of your day, especially during development.

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There's a classic experiment that I'd

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like to just briefly describe to you which

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has been performed in chickens.

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It's been performed in mice.

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It's also been performed on humans,

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where a visual occluder or a visual image.

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So an occluder is just a black screen or a piece of cardboard

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or an image, maybe some black and white checks or checkers,

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are placed at a certain distance from the eye,

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either up close or far away, and the impact

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of that on the length of the eyeball

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and on the structure of the lens and on the quality and acuity

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of vision is then measured.

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And to make a long story short, what these studies show is

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that, if during development, you or an animal

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exclusively looks at things that are up close, very

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close to the eye, and doesn't ever get long-range vision,

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the eyeball lengthens.

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And when that happens the lens, which, of course, is

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in the front of the eyeball, which

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focuses the light onto the back of the eyeball,

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which is where the so-called neural retina

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is, where the cells that sense light are,

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that visual image lands in front of as

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opposed to directly on the light-sensing portion

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of the eyeball that we call the neural retina.

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It lands too close or near the lens as opposed to

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on the back of the eyeball.

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And that's part of the reason what

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we call the consequence of that nearsighted myopia.

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In far sightedness, the opposite happens.

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The visual image is actually focused behind the retina.

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It doesn't land directly on the retina, which is what you want.

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It's focused too far behind the retina.

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And that's due to a shortening of the eyeball.

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So what I just described actually

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explains pretty well why kids who look at computer screens,

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or books up close often need glasses.

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When I was growing up, they called this nerd syndrome.

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Raising my hand for those of you that are listening.

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I read an awful lot, but I also spend time outside fortunately

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and running around on the soccer field

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and looking at things in the distance

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and playing in the neighborhood with my friends.

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Kids that spend the vast amount of their time looking

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at things up close, and particularly

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children who do that indoors for most of their waking time,

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well, those kids develop myopia.

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This is part of the reason why we

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have such an increase of the incidence of myopia nowadays.

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What's interesting, and I think most people don't realize,

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is that even as a young adult and adult, and perhaps even as

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an older adult, an elderly person,

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looking at things up close to much at the expense of getting

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some time viewing things at a distance,

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in particular outdoors, can be very problematic because it

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can exacerbate myopia.

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So the short, direct prescription

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here is to make sure that you're getting at least an hour or so

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each day, although ideally it would be more, of long viewing.

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And that could be done by walking outside and avoiding

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looking at your phone while walking.

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It doesn't require that you look at a particular object

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in the distance, although if you are scanning for and looking

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for objects in the distance, the way that you might on a hike

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or you're looking out toward or off a vista

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or you're looking for someone in the distance,

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all of that sort of visual scanning behavior

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is going to be very good for your eye health

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and for maintaining vision at a distance.

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If you're somebody who's far sighted

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and you have trouble seeing things up close,

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well, then you need to ask yourself whether or not

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you're spending too much time looking at things off

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in the distance, although I want to be very

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clear that nearsightedness and farsightedness aren't

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necessarily the consequence of this near, far viewing.

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There can be independent causes of nearsightedness

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and farsightedness.

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But for many people out there who

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are spending progressively more and more time just looking

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at things up close, you can get this lengthening

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of the eyeball or challenges in the way

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that the elasticity of the lens is controlled

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by the musculature in ways that make

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it hard to maintain sharp, crisp vision when you're

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looking at things at a distance or up close.

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So I can't, because there are simply no studies

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to support the idea that you need exactly two hours per day

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of outside long vision at a particular distance and/or

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that you want to cut off or have a threshold of four

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hours per day of looking at things up close,

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but we can say with a high degree of confidence

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that if you want to maintain or enhance

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your vision at all distances, that for every hour or so

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that you spend looking at things,

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say, a distance of 3 feet away or less,

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that you want to get at least one hour per day total, doesn't

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have to be all at once,

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of looking at things out in the distance

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or looking at things beyond 3 feet relative to the distance

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from your eye.

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So I think for some people who are already badly myopic,

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this isn't going to remedy that myopia.

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You're still going to need corrective lenses,

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but if you're somebody, similar to the person who

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asks the question, that they're quote unquote "noticing"

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their vision is deteriorating, really

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try and balance out the amount of viewing

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that you're doing at close distance and long distance.

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And, again, I would not obsess about the total numbers.

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It doesn't have to be three hours and three hours,

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but the more time that you can spend at viewing things

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that variable distance throughout the day,

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the better off you're going to be in maintaining and perhaps

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even enhancing your vision somewhat.

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Now, there's an additional behavioral tool

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that we can glean from the recent scientific literature

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exploring myopia which points to the fact

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that children who get two hours a day or more

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of time outside in sunlight--

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one of my favorite topics.

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I know many people are probably rolling their eyes

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right now when they hear me say you really

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want to view morning sunlight, not

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through a window or windshield.

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Don't wear sunglasses for that, trying to get as much sunlight

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as you can in your eyes early in the day.

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Never stare at any light so bright it's painful,

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look at, et cetera.

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We've done a lot of episodes on this.

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We have a Light for Health episode,

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this Isn't All the Sleep episodes.

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It's just such a basic foundation

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of circadian rhythm and health that I just keep repeating it.

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However, there are also large-scale clinical trials

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involving thousands of subjects that

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have shown that people, children in particular, who

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get two hours or more of outside time every day

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have a much lower incidence of myopia.

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Now, what's really interesting about these studies is that,

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while some of those kids are looking at things further

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off in the distance than they would if they were indoors

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on their tablets or screens or with their nose in a book,

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it does not seem to be the case that they

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have to be looking at things in the distance

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in order to see this reduced incidence of myopia.

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What's probably happening instead

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is that the particular wavelengths

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of light that emanate from the sun,

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that photon energy in particular is triggering

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the activation of the so-called intrinsically

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sensitive melanopsin and retinal ganglion cells, which we know

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are important for setting circadian rhythm for enhancing

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mood focus and alertness during the day

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and enhancing the quality and duration of sleep at night.

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But those melanopsin and intrinsically photosensitive

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ganglion cells are also involved in networks

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within the eye that relate to blood flow, that

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relate to the ciliary body, which

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is a structure within the eye that controls the aperture

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and movement of some key components

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within the eye, that also relate to the crispness of vision,

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that is the acuity of vision, at both short and long range.

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So there are a lot of technical details there.

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In fact, I really hope to get the great Russell Van

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Gelder, or Dr. Russell Van Gelder,

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who's the chair of ophthalmology at the University of Washington

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in Seattle, who is a world expert in this

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and the various aspects, both molecular and structural

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of the ciliary body and the lens,

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and he's an expert in uveitis, a very interesting topic

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in its own, to come onto the podcast

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and talk more about eye health.

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And we will do that in the not too distant future.

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Meanwhile, if the first behavioral protocol

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for enhancing and maintaining eye health

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is to make sure that you're spending at least some time

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balancing out the near vision and far vision during the day,

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it also stands to reason that you

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want to get outside for at least two hours a day,

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which I know sounds like a lot, in order to prevent myopia,

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if you're a young person, and offset the progression of

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and maybe even reverse some myopia,

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we don't know yet based on the data,

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but there's some indication that's

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possible, by getting outside two hours a day.

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And the cool thing is, because many people, including myself,

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have a lot of work to do and we need to be on our phones

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quite a lot, or we choose to be on our phones quite a lot,

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this effect of getting sunlight outdoors during the daytime

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for two hours or more does not seem

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to require that you stay off your phone or tablet,

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or that you're looking at things far in the distance

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the entire time.

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What this means is, if you can get

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outside onto a patio or a deck or an outdoor table if you can,

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if weather and conditions permit,

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and do some of your phone time and computer time and reading,

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et cetera, outdoors.

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Now, if you're already making an effort

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to get outside, hike, play sports, take walks,

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et cetera, that of course counts towards this two hour

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threshold.

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And I know this sounds like a lot, this two hours,

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and yet for most people, it certainly will vary,

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depending on time of year, but I think

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striving to get on average about two hours of outdoor time

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as much as you can or opening a window, which

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wouldn't be as good as getting outside, but opening a window

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and trying to get some natural light exposure to the eye

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to trigger the activity, these intrinsically

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photosensitive melanopsin and retinal ganglion cells, that's

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going to be a really good idea in trying to offset and maybe

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even reverse some vision loss.

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Now, the other behavioral protocols

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which have shown to be useful in terms of maintaining

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or improving vision relate to the musculature around the eye

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and the control of the movement of the lens.

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And actually, the lens of the eye has its own flexibility.

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It's a really, really interesting structure.

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I'll geek out on this far too long

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if I don't prevent myself from doing so,

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but the lens is just incredible.

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The fact that it has a specific structure of proteins

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like crystallines and things of that sort

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and that it can still derive nourishment from blood flow

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but does not actually have vasculature within it.

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So it's not-- if you notice the lens of your eyes

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and filled with blood vessels and capillaries

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because it needs light to pass through,

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super interesting structure I think

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the only violation of what I just said is the manatee.

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Those pigs are underwater, elephant-like creatures

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that I think were or are endangered.

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Down in Florida, they were getting chopped up

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by speedboats, but I think now there's

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some effort to preserve those big gentle giants.

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The manatee, as I recall, has a vascularized lens, which

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is why their eyes look opaque.

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It looks like they have cataracts.

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In any case, you're not a manatee.

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You have no blood vessel supply to the lens.

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Keeping that lens clear is vital nowadays.

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They can do lens replacement.

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There's really a pretty incredible progress

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in the realm of ophthalmology and surgical replacement

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of the lens or the cornea, other aspects of the eye.

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But if you're somebody who is interested in maintaining

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your vision, you're going to want

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to maintain the musculature that controls

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the movement and the change of shape in that lens

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and the movement of the eyes, which allows you to transition

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your vision from very sharp when viewing things

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up close to very sharp one viewing things at a distance.

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And this is where some of the so-called near-far exercises

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can be very useful.

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So when we did a full length podcast on eye health

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and improving eyesight, which I invite

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you to listen to if you like, talked

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about two different types of vision exercises that

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have been shown to be useful for improving vision

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at a level of acuity that have a lot

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to do with improving the musculature and the movement

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of the eyes and the lens.

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And that's what's called a smooth pursuit task.

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So you could go on to YouTube if you like and put smooth pursuit

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eye task and do this for a few minutes each day

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if you're trying to keep your vision strong.

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And what that task involves is, as the name suggests,

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smoothly tracking a small dot or crosshatch or arrow

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on the screen, which is very different

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than the so-called saccade type eye movements

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that we often make.

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Saccades are when you dart your eyes to a particular location

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to look at something that dart it to another location

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to look at something.

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Microsaccades are little, tiny versions

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of those that were doing most all of the time,

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believe it or not.

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When you look at a visual scene or image,

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if you did not have those little microsaccades,

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your brain would adapt or would attenuate

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to whatever you were looking at, and the visual image

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would actually disappear, which really

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speaks to how important it is that your perceptions change

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in order to maintain them.

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This is very similar to where if something

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is placed on your hand, say a finger,

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you'll notice that change, but then

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if you leave it there for a short while,

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you'll forget that it's there because the cells there

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have adapted out.

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There's no change.

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So your nervous system is largely responding to change.

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This is also why when you walk into a room

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and you'll often notice a novel smell,

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let's hope it's a good smell, after a few minutes

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or so, you don't notice the smell anymore

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because your olfactory system adapted that away.

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So a lot of that adaptation is prevented

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by those little microsaccades.

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And the macrosaccades, the bigger saccades,

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are really for moving your eyes around

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to look for things in visual space.

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Smooth pursuit is a very particular kind

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of visual behavior that you can do in a smooth pursuit

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task and zero cost.

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Costs a little bit of time I suppose to do this on YouTube.

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And most any of them will do.

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We can provide a link in the show note captions of one

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that we like or several that we like,

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but by doing that smooth pursuit task for a bit each day,

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maybe just a minute or two, you're

Time: 1106.11

maintaining your ability through the musculature of the eye

Time: 1109.83

to do smooth pursuit.

Time: 1111.27

And, of course, you do smooth pursuit

Time: 1113.19

when you move about your day, but for people

Time: 1115.11

that are trying to offset or reverse vision loss, doing

Time: 1117.6

some additional deliberate smooth pursuit exercises

Time: 1119.82

can be useful.

Time: 1120.67

The other visual exercise that can be very useful

Time: 1123.51

is the so-called near-far exercise.

Time: 1125.5

So this is best accomplished, I think,

Time: 1128.37

by holding out a pen or pencil in front of your eyes,

Time: 1133.44

in front of your head, and focusing very intensely

Time: 1135.537

through what's called a vergence eye movement, where you bring

Time: 1138.12

both eyes to the tip of the pen and then moving

Time: 1141.12

that pen closer and closer and closer to your eyes,

Time: 1145.11

where you get close enough that you actually

Time: 1148.41

have to deliberately bring your eyes--

Time: 1151.092

for those of you listening, this is

Time: 1152.55

what I'm doing right now-- to the point where it's blurry

Time: 1154.925

and you can no longer hold it in sharp, crisp relief.

Time: 1158.31

You can't see it sharply that is.

Time: 1159.685

And then you can move it out a little bit distance

Time: 1161.768

and play right around that threshold

Time: 1163.32

where it's hard to keep it in focus

Time: 1167.55

and then move it back out again.

Time: 1168.9

And then in doing that for even a minute or two, you'll find

Time: 1171.93

is a bit of a strain on your eyes,

Time: 1173.58

but you can actually build up the musculature

Time: 1175.56

and the neuromuscular connections that allow you

Time: 1177.69

to do that more efficiently.

Time: 1178.86

And that has been shown to improve

Time: 1180.66

certain aspects of vision, especially when people

Time: 1182.73

are diligent about doing those exercises,

Time: 1184.56

not necessarily every day, but let's say

Time: 1186.24

three days a week or so.

Time: 1187.38

They can be very fast.

Time: 1188.297

I actually find them fun for reasons

Time: 1189.87

that escape me entirely.

Time: 1191.683

Now, how close you can bring that object

Time: 1193.35

and still maintain it in sharp focus

Time: 1195.27

will vary from person to person based on a number of things.

Time: 1199.06

First of all, how healthy and well-performing

Time: 1202.56

their neural retina is, whether or not

Time: 1204.33

they have myopia or hyperopia, nearsightedness, et cetera,

Time: 1208.68

whether or not, for instance, you're

Time: 1211.92

like me and you have a fairly close inter pupillary distance,

Time: 1214.915

or whether or not you're more wall eyed

Time: 1216.54

and you have your eyes set further apart.

Time: 1218.248

All those things will dictate the exact performance

Time: 1220.86

of that task, but nonetheless, it's

Time: 1222.81

a very useful task to do when trying to maintain or improve

Time: 1225.67

vision.

Time: 1226.17

Now, of course, there are a lot more behavioral tools

Time: 1228.378

that one could use to maintain or enhance vision.

Time: 1230.49

I'm really touching on the biggest

Time: 1232.63

and what I consider the most important ones that

Time: 1234.63

are most accessible to people without the need

Time: 1236.547

for any fancy equipment at all.

Time: 1238.87

And if you want to learn more about other behavioral tools

Time: 1241.822

that one can use to maintain or enhance vision,

Time: 1243.78

please see the episode that we did on eyesight.

Time: 1245.82

You can simply go to hubermanlab.com.

Time: 1247.41

Put into the search function, eyesight or vision.

Time: 1249.775

It'll take you right to it.

Time: 1250.9

In fact, everything on that website is keyword indexed

Time: 1253.15

and will take you to the various episodes and time stamps

Time: 1256.35

that you're interested in according to that keyword.

Time: 1260.55

Now, the person who asked this question, who by the way,

Time: 1263.05

is Page Singer, thank you Page Singer,

Time: 1265.02

and the question got a lot of upvotes

Time: 1266.64

because apparently there's a lot of interest in this,

Time: 1269.37

understandably so, asked about nutrition and supplements

Time: 1272.82

for maintaining or improving vision.

Time: 1275.85

That could be a very lengthy conversation,

Time: 1277.62

but let's just summarize it with a few brief points

Time: 1279.9

that we know stand based on the clinical and scientific

Time: 1283.5

research.

Time: 1284.773

We've all heard that carrots are good for your eyes.

Time: 1286.94

Well, it's not carrots per se that are good for your eyes.

Time: 1289.43

It's vitamin A that's essential for the so-called

Time: 1292.25

phototransduction cascade.

Time: 1293.63

The phototransduction cascade is the process

Time: 1297.073

by which the photoreceptors, which

Time: 1298.49

are in the back of the retina, at least if you're human,

Time: 1301.04

they're in the back of the retina,

Time: 1302.75

take photons, light energy, and convert it

Time: 1304.91

into electrical signals that's then

Time: 1306.5

conveyed to the other cells and neurons within the retina

Time: 1309.8

and then passed into the brain to create visual perceps.

Time: 1312.98

Most people can't get enough of this fat soluble vitamin,

Time: 1316.13

we call vitamin A, by making sure

Time: 1318.59

that they eat at least some dark green leafy vegetables.

Time: 1322.04

And that they do that in their closest

Time: 1325.73

to raw form, maybe cooked a little bit

Time: 1327.83

but not overly cooked.

Time: 1329.092

There are other sources of vitamin A out.

Time: 1330.8

There you can look those up online just for sources

Time: 1333.59

of vitamin A. Most people will be able to get enough vitamin

Time: 1336.26

A from their nutrition and won't require it from a supplement,

Time: 1339.47

provided that it's not present at excessively high levels

Time: 1343.46

in a foundational supplement or vitamin mineral supplement.

Time: 1346.55

Getting some additional vitamin A

Time: 1348.23

from a foundational supplement or vitamin mineral supplement

Time: 1351.65

is probably not going to be an issue unless you really

Time: 1354.11

take in far too much of that vitamin

Time: 1356.36

A. It could potentially provide some insurance.

Time: 1358.58

But, again, I think most people can get enough vitamin

Time: 1360.83

A from their diet if they are taking carrots

Time: 1363.15

or to eat the foods that contain vitamin A,

Time: 1365.48

green leafy vegetables being one.

Time: 1367.25

The other food that's known to be highly enriched in vitamin A

Time: 1369.89

is liver, one of my least favorite foods regardless

Time: 1373.19

of what animal that liver comes from.

Time: 1374.96

Liver is somewhat of a popular/controversial organ

Time: 1379.31

meat in the nutrition space for reasons

Time: 1381.74

that aren't interesting, for sake of this discussion

Time: 1384.05

anyway I suppose for those of you

Time: 1385.903

that like liver, you could eat a little bit of liver

Time: 1388.07

every once in a while.

Time: 1388.987

It is rich in a number of things that are beneficial to health,

Time: 1391.843

although for you vegans out there,

Time: 1393.26

I'm sure you'll want to avoid liver entirely.

Time: 1395.312

I avoid liver because I just simply

Time: 1396.77

don't like the way it tastes.

Time: 1398.03

Maybe once or twice I've tasted liver

Time: 1399.59

that was appetizing to me.

Time: 1400.86

And it can be OK, but it's just not, or at least by my read it,

Time: 1404.33

can be OK, but it's not a food that I actively

Time: 1407.3

seek out, order, or prepare for myself on a regular basis.

Time: 1410.648

So fortunately, there are other sources of vitamin A as well.

Time: 1413.19

And, again, I just invite you to all put into a web search food

Time: 1417.8

sources of vitamin and figure out

Time: 1419.81

how to get your daily dose of vitamin A

Time: 1422.03

by taking in foods that you like for you.

Time: 1424.49

And then in terms of supplementation

Time: 1426.59

of things that can enhance vision, this is a newer area.

Time: 1430.17

And frankly, it's an area where most of the data

Time: 1432.62

point to some supplements that can potentially

Time: 1436.34

be beneficial in certain disease conditions.

Time: 1439.41

So for instance, in fairly progressed age-related macular

Time: 1443.45

degeneration.

Time: 1444.32

Age-related macular degeneration is

Time: 1446.15

fairly common, or more common than we would like,

Time: 1449.69

we should say.

Time: 1451.13

And it does appear that supplementing

Time: 1453.5

with certain things like lutein, which is present in eggs,

Time: 1457.85

or egg yolks in particular, especially egg yolks that

Time: 1460.22

aren't overly cooked, or that can be supplemented

Time: 1463.61

can potentially help with some instances

Time: 1467.84

of age-related macular degeneration.

Time: 1470.12

But the data on this are still emerging.

Time: 1471.83

I consulted with our chair of ophthalmology

Time: 1473.622

at Stanford about lutein and some of the other things

Time: 1476.09

that you'll see out there, like zeaxanthin and astaxanthins.

Time: 1479.3

And these xanthins come from certain fruits

Time: 1484.363

like blueberries, and they're present in supplements

Time: 1486.53

and things of that sort.

Time: 1487.55

The consensus I got talking to him

Time: 1490.54

and talking to some other ophthalmologists

Time: 1492.29

are that if you're really aiming to get a healthy diet,

Time: 1495.47

you're avoiding cigarette smoking.

Time: 1497.75

And by healthy diet I mean getting

Time: 1501.14

sufficient amounts of vitamin A and lutein

Time: 1503.12

through food sources.

Time: 1504.17

Again, you can look up where those food sources are,

Time: 1506.99

egg yolks just being one of them.

Time: 1509.215

Well, then chances are you're not

Time: 1510.59

going to need to supplement with lutein or the zeaxanthins

Time: 1514.43

or the astaxanthins.

Time: 1515.52

However, I have heard anecdotal reports from a number of people

Time: 1519.74

that they'll start taking a supplement for eye health,

Time: 1522.217

there are a number of them out there--

Time: 1523.8

we are not, as a podcast, affiliate

Time: 1525.38

with any of those eye health supplements by the way--

Time: 1527.78

and people are reporting enhanced vision.

Time: 1531.62

I receive emails all the time that say, I'm

Time: 1533.69

taking this lutein at 20 milligrams per day,

Time: 1536.78

and there I should mention that the dosage that's

Time: 1539.3

been explored in a couple of studies

Time: 1540.89

is 10 to 20 milligrams per day.

Time: 1542.58

Again, you could get that from foods.

Time: 1544.73

You could go above that if you're more cavalier,

Time: 1548.69

or you could go toward the lower end of that,

Time: 1551.33

10 to 20 milligrams per day, if you are somebody

Time: 1555.86

who's more conservative.

Time: 1556.98

I should say.

Time: 1557.76

Well, there aren't people out there who are,

Time: 1560.262

looking at lutein, they think it's fairly safe,

Time: 1562.22

and they're taking higher dosages of lutein,

Time: 1564.053

so 20 to 30 milligrams per day.

Time: 1565.46

They're also taking supplements that

Time: 1567.17

contain zeaxanthins and astaxanthins

Time: 1569.72

and are reporting anecdotally that their vision is enhanced.

Time: 1573.35

I don't dispute those claims, but as of now, there

Time: 1578.06

aren't many papers, I could only find about 4,

Time: 1581.66

3 really solid ones and then a fourth, that point

Time: 1585.86

to the specific disease instances

Time: 1587.9

where supplementing with lutein, zeaxanthin, or astaxanthin

Time: 1591.35

can be beneficial for slowing the progression of things

Time: 1593.84

like advanced onset age-related macular degeneration.

Time: 1597.02

And the degree of offset for that macular degeneration

Time: 1600.56

was slight.

Time: 1601.1

It wasn't enormous, but it was robust enough

Time: 1604.61

that it warranted reporting in the paper.

Time: 1607.28

Or things like Lieber's, which is a particular eye disease.

Time: 1609.8

It impacts a whole different set of systems in the eye.

Time: 1611.96

So basically, what I'm trying to say

Time: 1613.13

is, when it comes to supplements to support eye health,

Time: 1615.02

make sure you're getting enough vitamin A from your diet.

Time: 1617.395

If you're not, consider supplementation

Time: 1619.37

or consider changing your diet somewhat

Time: 1621.23

to make sure you can get that lutein and vitamin A.

Time: 1624.02

And if you are interested in it, and it's within your budget,

Time: 1627.02

I don't know of any evidence that supplementing

Time: 1631.1

with additional lutein, zeaxanthin, and astaxanthin

Time: 1634.01

can be dangerous at all.

Time: 1635.16

So for those of you that are really

Time: 1635.96

interested in maintaining or improving your vision,

Time: 1638.232

that might be an area that you want to explore.

Time: 1640.19

I personally am not taking lutein, zeaxanthin,

Time: 1643.16

or astaxanthin, at least not at this time.

Time: 1645.83

I do take a foundational supplement,

Time: 1648.26

which is my source of vitamin A in addition to my food sources.

Time: 1652.8

But I don't suffer from vision loss

Time: 1654.58

anywhere, readers at night, and I have for a long time.

Time: 1657.29

I have a little bit of a muscular weakness

Time: 1660.14

in one of my eyes that originated in childhood.

Time: 1663.578

So occasionally, if I get very fatigued, one of my eyes

Time: 1665.87

will deviate a little bit, a little bit

Time: 1667.495

of almost strabismus, especially if I've been awake

Time: 1670.67

for very long periods of time.

Time: 1672.2

It tends to recover once I get a good night's sleep.

Time: 1674.665

Some of you that have experienced

Time: 1676.04

this, where you have one eye that

Time: 1676.94

might just drift a little bit.

Time: 1678.02

I could do this for the camera if you want.

Time: 1679.43

OK, this is weird.

Time: 1680.36

I used to do this to my sister across the table when

Time: 1683.443

we were at a friend's houses for dinner.

Time: 1685.11

So I can actually move one of my eyes

Time: 1686.42

in like this, which actually just reflects

Time: 1688.28

that there's a extraocular muscle closer to my nose.

Time: 1692

It's rather weak, which allows me to do that.

Time: 1693.89

I can't do it so well with the opposite eye.

Time: 1696.14

Anyway, now I need to blink to clear my vision.

Time: 1698.18

But the point is that, if you're somebody

Time: 1700.4

who has a slightly deviating eye, slightly,

Time: 1704.48

often if you go to the ophthalmologist or optometrist,

Time: 1706.94

they're going to give you a prism lens which

Time: 1708.773

is going to redirect the image onto that slightly

Time: 1711.65

deflected eyeball.

Time: 1712.965

One thing you'll really want to discuss

Time: 1714.59

with that ophthalmologist or optometrist is whether or not

Time: 1718.76

there are exercises that you could do to overcome

Time: 1721.28

that issue without the need for a prism because what I saw

Time: 1724.58

and what many other people see when they put on a prism lens

Time: 1727.79

is that indeed it can line up their vision

Time: 1730.37

or their visual perception better,

Time: 1732.08

but indeed, it can lead to progressive weakening

Time: 1734.84

of the muscle further and further.

Time: 1736.83

So then that eyeball starts to deviate further and further.

Time: 1739.4

And that raises a larger question, which is,

Time: 1741.59

should we wear corrective lenses?

Time: 1743.48

In fact, if you go online, you'll

Time: 1744.86

find or hear about these examples

Time: 1746.48

of people that stopped wearing their corrective lenses,

Time: 1748.82

their glasses or contacts, in order

Time: 1750.65

to bring their vision back or improve

Time: 1752.75

their vision on their own.

Time: 1754.107

Now, if your vision is quite impaired,

Time: 1755.69

you're going to need corrective lenses or contacts.

Time: 1757.842

However, there are a number of people out there

Time: 1759.8

who find that if their vision is somewhat impaired,

Time: 1763.34

that forcing themselves to view things at a distance

Time: 1766.22

to do smooth pursuit, to do near far,

Time: 1768.95

and to make sure that they're getting adequate nutrition

Time: 1771.59

and things of that sort, can all sum

Time: 1774.47

to help offset some of the visual impairment that would

Time: 1777.53

occur if they were to just pop glasses on their face

Time: 1780.84

and rely on the corrective lenses

Time: 1783.05

in order to focus the light onto the correct area within the eye

Time: 1786.92

onto the neural retina.

Time: 1788.06

So I'm not telling people to throw off or get rid

Time: 1790.64

of their corrective lenses and contacts,

Time: 1792.74

but you can be overly reliant on these things, like a crutch,

Time: 1796.31

in a way that perhaps you want to do a little bit of work

Time: 1798.735

to try and overcome and then maybe work

Time: 1800.36

with a weaker prescription.

Time: 1801.5

And certainly, in the case of prism lenses,

Time: 1804.08

what I mentioned before is a real consideration.

Time: 1806.117

It's one I'm very familiar with.

Time: 1807.45

So as a last but I think very important

Time: 1809.57

and exciting feature of visual improvement is red light.

Time: 1813.785

I talked a little bit about this on the episode of the Huberman

Time: 1816.41

Lab podcast all about light and health.

Time: 1818.51

There's some really spectacular, I

Time: 1820.34

think I consider it spectacular, many other people consider

Time: 1823.07

it spectacular, research out of University College London.

Time: 1825.89

And the work I'm referring to is Glenn Jeffrey's work.

Time: 1828.35

I've known Glenn for a long time.

Time: 1829.73

These are animal studies, and now two human studies,

Time: 1832.55

exploring how exposure to red light early in the day

Time: 1837.89

can offset some of the vision loss related

Time: 1840.68

to age-related macular degeneration, or simply

Time: 1843.59

age-related visual decline.

Time: 1845.378

There's a whole mechanism here that's

Time: 1846.92

discussed in that episode, but it has to do with the fact

Time: 1849.295

that red light and near-infrared light, together, or maybe

Time: 1853.7

even separately, when viewed for even just a minute

Time: 1856.25

to 3 minutes once, or maybe two or three times per week

Time: 1860.21

maximum, can actually reduce the number of what

Time: 1864.23

are called reactive oxygen species in the photoreceptors

Time: 1866.57

that convert photons into electrical signals

Time: 1868.34

the rest of the visual system can understand.

Time: 1869.81

So that's a mouthful.

Time: 1870.84

Basically what they found was, for people 40 years or older,

Time: 1876.6

if they viewed this red light at a distance of about

Time: 1880.417

a foot and a half, although I wouldn't

Time: 1882

get too specific with this, for a few minutes each week total,

Time: 1886.59

they were able to offset some of the vision loss

Time: 1888.72

within a particular domain of vision.

Time: 1891.237

And I don't have time to go into the details

Time: 1893.07

here because I do that in the Light for Health episode,

Time: 1895.77

but you have different types of photoreceptors, cones,

Time: 1898.69

and rods.

Time: 1899.19

You have different types of cone photoreceptors

Time: 1901.08

that respond to different wavelengths of light,

Time: 1903.03

short, medium, and long wavelengths of light

Time: 1904.863

so-called blue, green, and red cones,

Time: 1908.16

they're sometimes called.

Time: 1909.66

When these people who are 40 years or older

Time: 1912

viewed red light on a consistent basis early in the day,

Time: 1915

and it did have to be early in the day,

Time: 1916.8

there was a real circadian effect there,

Time: 1918.66

there was a offset of some of the vision loss

Time: 1923.12

that would normally occur in a particular wavelength

Time: 1926.18

of light range that resulted in better visual acuity overall.

Time: 1930.66

So if you're very concerned about your vision,

Time: 1932.66

or you're into red light therapies, et cetera,

Time: 1935.33

there are a number of different red light devices out there.

Time: 1938.63

At some future point, the Huberman Lab podcast

Time: 1940.88

may partner with one of these red light companies.

Time: 1943.297

So right now, I'm not going to mention any of them

Time: 1945.38

in particular.

Time: 1945.77

They're prominent online.

Time: 1946.97

What you're looking for is a red light unit that provides

Time: 1949.85

red light and maybe far--

Time: 1951.35

near infrared-- excuse me-- light as well.

Time: 1954.12

So something in the 650 to 720 ish nanometer range.

Time: 1960.18

So really it's going to look red or almost invisible

Time: 1962.51

to you if it's really far into the infrared.

Time: 1965.42

And you'll want to view that at a distance of about

Time: 1968.603

a foot and a half to 2 feet.

Time: 1969.77

And you don't want it to be so bright

Time: 1970.94

that it's painful to look at because you

Time: 1972.38

don't want to damage your eyes.

Time: 1973.47

But that's essentially what they used in these studies

Time: 1975.735

from the Jeffrey lab.

Time: 1976.61

And they showed some pretty impressive

Time: 1978.32

offset of some of the aspects of vision loss

Time: 1981.29

in these people 40 and older.

Time: 1982.53

So that's an area that you may want

Time: 1984.11

to explore as well, especially for folks 40 and older.

Time: 1987.38

And, again, this red light exposure

Time: 1989.15

had to be done early in the day.

Time: 1990.5

So hopefully, that collection of behavioral tools near, far,

Time: 1993.65

smooth pursuit, some of the discussion about lutein,

Time: 1996.35

nutrition, vitamin A, supplementation, zeaxanthins,

Time: 1999.14

astaxanthins, getting two hours of light exposure

Time: 2002.98

outside, sunlight exposure, get outside to do some

Time: 2005.35

of your work, and perhaps even deliberate red light exposure

Time: 2009.52

for certain people can be used to offset your concerns

Time: 2013.78

and your action potential vision loss

Time: 2016.66

and maybe even improve your vision regardless of what age

Time: 2019.18

you are.

Time: 2019.78

Everything I described is supported

Time: 2021.31

from the Peer-reviewed literature.

Time: 2022.99

And, again, if you want to get the deep dive on mechanism

Time: 2025.57

and further information about dosages,

Time: 2027.94

please check out the episode on eyesight

Time: 2030.51

and improving your eyesight and the Light for Health episode

Time: 2033.01

again at hubermanlab.com.

Time: 2034.96

Thank you for joining for the beginning

Time: 2036.7

of this Ask Me Anything episode.

Time: 2038.5

To hear the full episode and to hear future episodes of these

Time: 2042.37

Ask Me Anything sessions, plus to receive transcripts of them

Time: 2045.88

and transcripts of the Huberman Lab podcast standard channel

Time: 2049.03

and premium tools not released anywhere else,

Time: 2052.03

please go to hubermanlab.com/premium.

Time: 2054.975

Just to remind you why we launched the Huberman Lab

Time: 2057.1

podcast premium channel, it's really twofold.

Time: 2059.6

First of all, it's to raise support

Time: 2061.42

for the standard Huberman Lab podcast channel, which,

Time: 2064.33

of course, will still be continued to be released

Time: 2066.88

every Monday in full length.

Time: 2068.488

We are not going to change the format

Time: 2070.03

or anything about the standard Huberman Lab podcast,

Time: 2073.51

and to fund research, in particular research done

Time: 2076.3

on human beings, so not animal models

Time: 2078.219

but on human beings, which I think we all agree

Time: 2080.409

is the species that we are most interested in.

Time: 2082.96

And we are going to specifically fund

Time: 2085.36

research that is aimed toward developing

Time: 2087.79

further protocols for mental health, physical health,

Time: 2090.153

and performance.

Time: 2090.82

And those protocols will be distributed

Time: 2092.71

through all channels, not just the premium channel

Time: 2094.933

but through all channels, Huberman Lab podcast

Time: 2096.85

and other media channels.

Time: 2098.24

So the idea here is to give you information to your burning

Time: 2101.32

questions, in depth, and allow you the opportunity

Time: 2104.47

to support the kind of research that

Time: 2106.3

provides those kinds of answers in the first place.

Time: 2108.683

Now, an especially exciting feature of the premium channel

Time: 2111.1

is that the tiny foundation has generously

Time: 2113.65

offered to do dollar-for-dollar match on all funds raised

Time: 2116.92

for research through the premium channel.

Time: 2119.45

So this is a terrific way that they're

Time: 2121.18

going to amplify whatever funds come in through the premium

Time: 2123.638

channel to further support research for science

Time: 2125.928

and science-related tools for mental health, physical health,

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and performance.

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If you'd like to sign up for the Huberman Lab Premium channel,

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again, there's a cost of $10 per month,

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or you can pay $100 up front for the entire year.

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That will give you access to all the AMAs.

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You can ask questions and get answers to your questions,

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and you'll, of course, get answers to all the questions

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that other people ask as well.

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There will also be some premium content such as transcripts

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of the AMAs and various transcripts and protocols

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of Huberman Lab podcast episodes and not found elsewhere.

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And, again, you'll be supporting research

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for mental health, physical health, and performance.

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You can sign up for the premium channel by going

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to hubermanlab.com/premium.

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Again, that's hubermanlab.com/premium.

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And as always, thank you for your interest in science.

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